Hi Covers,

As part of the process of preparing to comply with the FDA aseptic guidelines I need to justify the choice of a stainless steel biological indicator (BI) carrier (page 29).

I am looking for any references/experience anyone may have concerning the effects that the BI substrate may have on the resistance (D value & Z value) of Geobacillus stearothermophilus to a standard steam cycle (121 C)

I want to find out which substrates increase resistance above the typical stainless steel carrier. I would especially like to know what effect a paper substrate may have in a steam sterilization process.

Any help/guidance gratefully received,

Thanks,

Jimmy

Any takers ?

Heck no! I'm still trying to figure out how to pronounce "Geobacillus stearothermophilus":lol::lmao:

But I sincerely hope we do have someone here who can help..........I'll see if we have anyone at NQA-USA who knows this type of thing, too!:agree1: