While performing the cleaning validation is it required to evaluate the cleaning method all the times by Swab, Rinse and Visual?

The reason why the above question came is:

we are having a kilo lab facility where we can able to manufacture the material with low volume (where regulatory filing is also possible/happened from this facility). The facility consist of small glass vessel where in some cases it is not possible to perform swab sampling.

In such cases can we go by Rinse and visual? (by avoiding swab)

Also it will be helpful if there is any regulatory reference for this.

Thanks,

Regards / Raghu

Is this a pharmaceutical, food production, or some other regulated industry?

When on ship, eons ago, we did basic particulate checks with a black light. The black light would pick up film contamination as well. However, this would only be acceptable in certain industries and applications. We'd need to start by understanding what this cleanliness is for.

It is an API (Active Pharmaceutical Ingredient) industry.

Regards / Raghu