I'm in month 5 of my new Quality Manager prosition and have to say it depends on what you are walking into the middle of. I came in replacing a manager that had given up and let everything slide so have spent 4 months establishing ground zero and rebuilding. But three things to do is
1) make sure what they are expecting of you
2) learn your quality manual and procedures
3) take a step back and assess how things are going and what is being done now from a complete fresh set of eye. Write down everything you observe both good and bad.
I found it helpful to assess everything first off because my view was not yet tainted by what everyone called "how we've always done it". How it's done may be right but without things ever being questioned things can never be improved.
Best of luck in your new position and when you need help feel free to ask. someone around may have a solution.