I'd suggest either of the following 2 approaches (or combination, as suitable):
1. For any particular process, list all requirements for each market, and develop your system procedures to reflect the strictest requirements.
- An example of this is record-retention periods - our system procedures simply require the strictest requirements amongst all our markets (not a big deal, because most of our records are maintained electronically).
2. Create general procedures, and in an appendix or table specify any additional or particular requirements needed for specific markets. For example, our Post-Market Vigilance procedure has a general requirements for how we handle reporting, recall, advisory notices etc., and then an appendix describing any additional or variant instructions/forms/information/timeframes etc. that are unique to each market (Europe, US, Australia, Canada,...etc.).