For clarification, you're talking about a trace matrix of product design inputs to design outputs / test?
If so, there are tools outside an eQMS that can be used; e.g., DOORS (requires fairly substantial amount of care and feeding) & Polarion (less overhead and less expensive than DOORs but still requires a good deal of setup). Both allow customization to pretty much do anything you want. I have one client using RMTrack. Low cost but is a bit more manual in terms of setting up and maintaining relationships. (I don't work for any of the companies providing the tools and certainly don't get any sales royalties!). I've been told that Jira can be configured (maybe with plugins?) to facilitate tracing but I don't have any experience.