TarKEpa,
Follow Wes Bucey's advice: contact your auditor for clarification! As you can see so far, there are many interpretations of the same statement.
I am going to assume that you are following ISO 13485, being a pharmaceutical organization. If that is the case, there is no requirement in the standard to determine the "number of changes in the documents after which reissuing takes place [...]" (see clause 4.3 for requirements). Therefore the auditor' comment cannot be more that an opportunity for improvement for your procedure and/or document control process. At this point you can ignore it (if the system is suitable and compliant) or take action (if you see the opportunity as well). Whatever you decide to do, and at the risk of repeating myslef, contact your auditor for clarification first!!!