We have used GAGEtrak in our manufacturing setting with roughly 175 employees and thousands of gages.
http://www.cybermetrics.com/en/products/gagetrak/index.html
It can be run as a self contained system on a single computer/user and scaled up as needed over time to accommodate more users integrated with a Microsoft SQL Server (sold separately). The interface is designed around Access software so it should be familiar to most Microsoft Office users. It does not require Office to be installed to function (all the required run-time libraries are included).
The amount of "required" data to form a functioning system is kept to a minimum so you can quickly begin using the program with little setup. There are several advance features available though to suit even the most demanding systems. We don't need it for our business but there is even a specific installation to meet medical requirements (21 CFR Part 11).
As of today (6/17/2015), up front cost for a single-user license is $2,000, with the option for annual Maintenance Agreements ($399/1 year, $699/2 years) to keep the software current and have access to support. Licenses are perpetual though, so if you opt for no maintenance there is no recurring cost.
We have used this software for the past 15+ years. Support has been good from my experience.