Increased application of Hotelling T sq and its use within manufacturing warrant examination of violations of basic statistics assumptions. Over 80 percent of industrial processes violate these assumptions. Hotelling T sq assumes normally distributed and independently sampled data. Process control decisions on defect detection, adjustment of manufacturing processes, or on modifications to manufacturing equipment, are all subject to expensive mistakes if supporting statistical methods are applied invalidly. This paper discusses assumptions violations and techniques to prepare manufacturing data for valid application of Hotelling T sq, and additionally for principal components analysis, which is often used in conjunction with Hotelling T sq. Violation conditions, effects and remedies are tested and illustrated.