Nanomaterials? Products based on human cell or tissue derivatives?

#1
Could somebody please give me some examples of products that, according to the MDR new definitions, include:

-nanomaterials, or
-are based on human cell or tissue derivatives.

Thanks!
 
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yodon

Staff member
Super Moderator
#2
I'll start out by saying "I have no idea" but it seems like an interesting discussion so I'll jump in.

Regarding nanomaterials, the definition in the MDR seems a good starting point:

‘nanomaterial’ means a natural, incidental or manufactured material containing particles in an unbound state or as an aggregate or as an agglomerate and where, for 50 % or more of the particles in the number size distribution, one or more external dimensions is in the size range 1-100 nm;

Fullerenes, graphene flakes and single-wall carbon nanotubes with one or more external dimensions below 1 nm shall also be deemed to be nanomaterials;


As far as products based on human cells, I don't know if this qualifies but I've seen reports of '3-D printers' depositing skin cells (for wound care I think).
 

Ninja

Looking for Reality
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#3
I don't know much about the MDR, but I've been working with nanomaterials for a couple of decades...
They used to be call "sub-micron"...but "Nanoparticle" was sexier and got much more government funding.

I'm in ceramic processing, and ceramic strength increases (typically) with smaller grains.
Alumina (Al2O3) goes translucent...almost transparent...when the grains are small enough (or large enough)...read "great armored windows".
And thermal shock resistance improves (read torch nozzles and blast furnace ladles and crucibles).

Finer and finer ceramic particles also mean lower firing temperature...read "I can make an Al2O3 and gold integrated circuit, instead of having to use platinum which costs more.

Catalysis (read catalytic converter, gas sensing, vapor sensing, explosives residue detection at the airport, etc.) works by exposed surface...finer particle = more surface...

There are hundreds of ceramic nanoparticles (Al2O3, ZrO2, fume silica for dessicants, TiO2 for paint opacifiers, paper coatings to render higher quality images (less ink bleed), holograms printed onto beer bottles and windows, transparent solar cells (nano-silver particles to harvest power, but so fine you can't see them), etc.

Again, I don't know much about MDR...but these are the tip of the iceberg when it comes to nanoparticles currently market available.

Sumitomo Specialty Chemicals alpha alumina is available with particle sizes down to 30nm. Makes a nice smooth fired surface for magnetic recording media...or as a catalyst support for hydrogen separation...

HTH...I do not work for Sumitomo...
 
#4
Very interesting, I have also read that custom-made prosthesis are being made with 3D-printing. There is a technique called SLS, not sure if the size of the particles will fall into the nanomaterials category.
 
#5
Very interesting input, in which kind of medical devices will then these materials be used? Still trying to picture concrete examples of devices that may be affected by the MDR nanomaterial definition.
 

Ninja

Looking for Reality
Trusted Information Resource
#6
Search terms to guide your search:

Forget "3D Printing"...that already had it's round in government funding...look for "Additive manufacturing" now...same thing, but free money guides vocabulary when new technologies are involved...

SLS (Selective Laser Sintering) is not printing...but is {sort of} an additive manufacturing process.
DOD (Drop on demand), UV matrix curing, LOM (Layered object manufacturing) and many many others are all swept together into "Additive Manufacturing".

Additive Manufacturing does not require nanomaterials...but nanomaterials can be used in an additive manufacturing process.

Nano particle suspension for diabetic blood testing...is this the example you are looking for? Or an ammonia sensor to breathe on to check glucose vs insulin ratio? Both of these use may nanoparticles in the sensing operation...

more surface = more catalysis = higher response signal = can use less material = cheaper/lighter/faster/disposable...
 
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