SBS - The best value in QMS software

Relationship between Blend Uniformity and Content Uniformity

Ajit Basrur

Ajit Basrur

Staff member
Admin
#1
#1
During the manufacture of Oral Solid Dosages (like tablets), I often hear divergent views on the relationship between Blend Uniformity and Content Uniformity.

What do you feel - could a statistical correlation amongst them be established or not ?
 
Popular whitepapers from DISCUS
Elsmar Forum Sponsor
R

Reiko Shiratori

#3
#3
Sorry for late response, I found this thread today.

This is a difficult question to me, (I'm not in pharmaceutical industry) but I guess,

Blend Uniformity: in other word, homogeneity.

Content Uniformity: the amount of drug in each tablet is same.

I hope my understanding is right, but I would like to know other Cover's thoughts.


Reiko:)
 
You must log in or register to reply here.
Thread starter Similar threads Forum Replies Date
T Relationship between ISO 9001 and ISO – IEC BS EN 870079- 34 2020 ISO 9000, ISO 9001, and ISO 9004 Quality Management Systems Standards 5
S Relationship between IEC 62304 problem resolution and ISO 13485 IEC 62304 - Medical Device Software Life Cycle Processes 8
C Understanding the relationship between 62304 and the MDD ER IEC 62304 - Medical Device Software Life Cycle Processes 7
D Relationship between Diameter and Flow Rate & the Length Statistical Analysis Tools, Techniques and SPC 3
T Relationship between ISO9001 and Lean Lean in Manufacturing and Service Industries 15
P The relationship between SPC and a Quality Management System Statistical Analysis Tools, Techniques and SPC 4
T Relationship between TS16949 and 5 Core Tools & relationship between 5 Core Tools IATF 16949 - Automotive Quality Systems Standard 5
N What is the relationship between a DFMEA and PFMEA? FMEA and Control Plans 1
Q What is the relationship between Standard Deviation and 6 Sigma? ISO 9000, ISO 9001, and ISO 9004 Quality Management Systems Standards 4
J Relationship between Quality, Reliability, Price and Delivery Misc. Quality Assurance and Business Systems Related Topics 7
D AIAG FMEA 4? Ed. Explanation: Relationship between PFMEA and Special Characteristics FMEA and Control Plans 8
S Relationship between Normal Distribution and AQL AQL - Acceptable Quality Level 13
D Relationship between IEC 60601-1 3rd Ed and IEC 60601-2-10 IEC 60601 - Medical Electrical Equipment Safety Standards Series 8
S The relationship between IEC 60601-2-18 and IEC 60601-2-37 - Ultrasound Project IEC 60601 - Medical Electrical Equipment Safety Standards Series 2
P Relationship between Crimping ID & Crimping Depth - Minitab usage Statistical Analysis Tools, Techniques and SPC 3
kedarg6500 Relationship between Cp and Cpk Capability, Accuracy and Stability - Processes, Machines, etc. 4
L Arima Output - Relationship between my raw data and the residuals generated Using Minitab Software 1
C The relationship between OEM and the subcontracted manufacturer 21 CFR Part 820 - US FDA Quality System Regulations (QSR) 1
D Relationship between ISO 9001:2000 and EFQM ISO 9000, ISO 9001, and ISO 9004 Quality Management Systems Standards 2
L What's the relationship between LVD (low voltage directive) and MDD EU Medical Device Regulations 3
D The relationship between the FMEA and Control Plan FMEA and Control Plans 4
K Relationship between "Corrections/Removals" procedure and "Recall" procedure US Food and Drug Administration (FDA) 11
M Relationship between APQP and CM (Configuration Management) APQP and PPAP 11
S Relationship and Differences between ISO 16949 and ISO 15504 (SPICE) IATF 16949 - Automotive Quality Systems Standard 3
kedarg6500 Relationship between Cp & Cpk Statistical Analysis Tools, Techniques and SPC 5
M Relationship between quality assurance costs and failure costs Quality Tools, Improvement and Analysis 4
L Relationship between Calibration and a Gage R&R study? General Measurement Device and Calibration Topics 9
V Relationship between Severity and Class FMEA and Control Plans 3
D Relationship between ANOVA and measurement accuracy - Mechanical strenth of a closure Statistical Analysis Tools, Techniques and SPC 13
A ISO TS 16949 - Relationship between requirements and processes IATF 16949 - Automotive Quality Systems Standard 0
J FMEA - What is the relationship between Detection and Prevention? QP Newbie question. FMEA and Control Plans 12
J Relationship Between SAP and ISO9001:2000 Quality Assurance and Compliance Software Tools and Solutions 1
P The relationship between ISO 17025 vs. ANSI Z540-1 ISO 17025 related Discussions 2
L Is there any relationship between Cpk & Right First Time? First Pass Yield (FPY)? Capability, Accuracy and Stability - Processes, Machines, etc. 4
L 'Distributor' definition & MDR/MSR relationship EU Medical Device Regulations 3
S APQP Relationship Diagram APQP and PPAP 2
J CEN/TR 17223:2018 Guidance on the relationship between13485 and MDR.. worth the money?? ISO 13485:2016 - Medical Device Quality Management Systems 2
K Does OEM/OBL-Relationship need to involve an EU Authorized Representative? EU Medical Device Regulations 11
MDD_QNA What is the relationship with the CSA group? Canada Medical Device Regulations 10
T ITAR/EAR relationship and Flow Down to Suppliers AS9100, IAQG, NADCAP and Aerospace related Standards and Requirements 5
C DFMEA vs. PFMEA Relationship: The cause in DFMEA becomes Failure in the PFMEA FMEA and Control Plans 2
J Responsibilities, Authorities and Relationships - What does Relationship mean? ISO 9000, ISO 9001, and ISO 9004 Quality Management Systems Standards 4
5 ISO 13485 relationship to 21 CFR 820 ISO 13485:2016 - Medical Device Quality Management Systems 17
alonFAI Definition Failure Review Board and FRACAS - Relationship and differences Definitions, Acronyms, Abbreviations and Interpretations Listed Alphabetically 2
T Capability Level Relationship with ISO/IEC 20000 Achievement IT (Information Technology) Service Management 2
N Agile 9.3.1 Relationship Searches - Meaning of Message Manufacturing and Related Processes 1
C CRMs (Customer Relationship Management) to help achieve ISO 9001 ISO 9000, ISO 9001, and ISO 9004 Quality Management Systems Standards 6
C ISO9001 and ISO 13485 Relationship? Can we do both effectively? ISO 9000, ISO 9001, and ISO 9004 Quality Management Systems Standards 4
B Relationship Pictures Coffee Break and Water Cooler Discussions 10
shimonv Operator vs. Manufacturer Relationship and ISO 13485 / CE Requirements ISO 13485:2016 - Medical Device Quality Management Systems 5

Similar threads

Top Bottom