Back in the 1980's I was working with complex aviation electronics. I can not find the old file but it shows a component failure that we were seeing consistently. It took a lot of testing and IR temperature 'photos' before we identified the actual root cause. An upstream component was causing intermittent voltage spikes which killed a downstream component. All these years later I can not remember why that component was failing, but I remember we did find the cause. Complex systems are problematic to identify a definite root cause in.