You will obtain the same results from each. Regression is an older version that retains a lot of manual control for those that are very adept at regression analysis. However, as reynald indicated, to include interactions (and quadratics) you must manually create these factors in their own columns.
General Regression is a recent addition that is more user-friendly. To create an interaction, you simply add A*B to the model with no need to create the factor in a column.
In Minitab 17, both were consolidated into a single option.